Educational information only. Not medical advice, not a diagnosis, and not an offer to sell any product. These are experimental or unapproved substances; we do not provide dosage, sourcing, or use guidance. Consult a licensed clinician. We link to official sources only.
| Peptide | Nominated for | FDA staff position | Outcome |
|---|---|---|---|
| Body Protection Compound 157 | Ulcerative colitis (other referenced uses deemed insufficiently supported) | Staff briefing proposed NOT adding | Pending vote (July 23-24, 2026) |
| Thymosin beta-4 fragment | Wound healing (lyophilized powder for injection) | Staff briefing proposed NOT adding | Pending vote (July 23-24, 2026) |
| Mitochondrial-derived peptide | Obesity; osteoporosis | Staff briefing proposed NOT adding | Pending vote (July 23-24, 2026) |
| Lysine-proline-valine tripeptide | Wound healing; inflammatory conditions (topical cream/gel) | Staff briefing proposed NOT adding | Pending vote (July 23-24, 2026) |
| ACTH-fragment heptapeptide | Cerebral ischemia; migraine; trigeminal neuralgia | Staff briefing proposed NOT adding | Pending vote (July 23-24, 2026) |
| Epithalon | Insomnia (SC injection) | Staff briefing proposed NOT adding | Pending vote (July 23-24, 2026) |
| Delta Sleep-Inducing Peptide | Opioid withdrawal; chronic insomnia; narcolepsy | Staff briefing proposed NOT adding | Pending vote (July 23-24, 2026) |
The PCAC advises the FDA on which bulk substances may be used in compounded medicines. Several performance and longevity peptides were nominated; FDA staff briefing documents proposed not adding most of them, citing gaps in characterization, human safety, and effectiveness.
It means the substance is not endorsed for compounded human use through this pathway. It does not make it a supplement, and it does not establish safety or efficacy. Marketing claims implying treatment or recovery remain high-risk.
Watch the difference between what was NOMINATED (marketing hopes) and what the FDA staff briefing ACTUALLY supported (usually far less). Evidence grade, not enthusiasm, is the signal.
The committee reviewed whether to allow them in compounding. 'Not added' is not the same as a formal ban, but it means no endorsement for compounded human use.
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Educational information only. Not medical advice, not a diagnosis, and not an offer to sell any product. These are experimental or unapproved substances; we do not provide dosage, sourcing, or use guidance. Consult a licensed clinician. We link to official sources only.