Peptide Radar

Epitalon: evidence, claims & regulatory status

PR
Peptide Radar Research Desk
Independent evidence aggregator. Not a clinic, not medical advice. · Updated 2026-07-21 · How we grade evidence

Longevity & sleep PCAC: Committee vote pending (July 23-24, 2026)

A synthetic tetrapeptide linked to longevity and telomere marketing. FDA noted a lack of human safety/effectiveness support and proposed not adding it.

Educational information only. Not medical advice, not a diagnosis, and not an offer to sell any product. These are experimental or unapproved substances; we do not provide dosage, sourcing, or use guidance. Consult a licensed clinician. We link to official sources only.

What it is

A synthetic tetrapeptide (Ala-Glu-Asp-Gly) linked in market copy to pineal-peptide and anti-aging ideas. Human evidence is weak.

Also known as: Epithalon, Ala-Glu-Asp-Gly tetrapeptide

Why people search it now

Strong longevity and anti-aging curiosity; high hype risk.

Claims by evidence grade

ClaimStrongest evidence
Longevity / anti-agingD Cell / mechanistic
Sleep / insomniaR Regulatory only

Regulatory status

FDA distinguished epitalon from epithalamin, noted lack of safety/effectiveness support for humans, and proposed not adding it.

Known risks & evidence gaps

Longevity claims rest on weak evidence. High marketing hype relative to data.

FAQ

Does epitalon extend lifespan?

There is no reliable human evidence for lifespan claims; support is weak and mechanistic.

Official sources

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Educational information only. Not medical advice, not a diagnosis, and not an offer to sell any product. These are experimental or unapproved substances; we do not provide dosage, sourcing, or use guidance. Consult a licensed clinician. We link to official sources only.